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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32742386302a9a7e34fc38e162d2f6d8d28cfeead01f6cc85b27b23b633b5974' 
  AND token = 'wAa/wrPv0RCCtN52ecn5vTVl2QhOCWdl517sEjC29Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}