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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a5b00b0265e48d66c18e7359e50dece592b482221fe3019156447e24882c5af' 
  AND token = 'euFdbQRlD3Hs+7Lp3RCa0XG8c2yEpU/umdjtytk+QZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}