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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a95c53963c585268a7433b5a83c58a89e9bb776cec07e1e39bf2301f4d8e5e86' 
  AND token = 'XTe9WDEumu2L7stF33wG9VuPmiq4Dm5kTapUv83nUE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}