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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65d09482a206d3e1fbbbe2b080dae7fd5ffbd210fde9f7ed6f9759e406787da6' 
  AND token = 'eeRGxvjZHQCRY2+clYFY6AO+nUIeMoRmeWzxxgtTVGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}