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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4db1970acb9f423291715a0f16443212d9c80f1e7648e4444cbd1272543d7050' 
  AND token = '3yVOfelLEV1tsfm8FlcvZszxmopMJmeBDWrm7NOdjU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}