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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15be23d53246448bb4511b8e5d00761285e81aaf0f56d8f638687a131cf64f6a' 
  AND token = 'OQD+CRNQD7EEu3JaZihdQiFYxN2XOP2yLHh+sXqOLRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}