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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eceff40acdbf9b96e3c0aee49b4b9c4dbc22c73711f0528a170473750d8f017' 
  AND token = '391JD7jOWyHw0kH3uGvDmTExwB8kRLcdHNFbX2XdMho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}