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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd74ebed822da1f2b63abc80656abf7f5def1660f409fbbdcf3c904f90bddf7a' 
  AND token = 'xTi117D0qJGI5/gUkw0TyKgyx7kCzAyrHqnXzeqXcig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}