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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51f42b8d7a6362b55b828653e51aba5302529dede03fc221166dc45d3b67aabe' 
  AND token = 'ip6VSSN59qGNY7J6FkGxn12jmznyHZrPq7TWW7wKZUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}