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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8063dffef0c3028468a79bfb8248b71131cc562c01bc8e5bd00d2429f643744' 
  AND token = 'uLG1BDq/kkDc9L3+Wsgm1xH5esvV6SaPA1Qrz2rA4kQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}