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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f8f85edf204a2564d4040e2b0744b6fe0810f17b2702395017a480309f2a154' 
  AND token = 'DMEVfCpUihlJ8yj2rAvVcbRQr7HgXMX2QM5WUaQUOxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}