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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53b860e68b1f1cbfb56de9507255f3b7ba710221023aeb1fef2b8310bab30d90' 
  AND token = 'IAERIJbbnuuhiDPobZnOVV953Xa+wvIi1DkyzwtA/zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}