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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17c83463add060165a0bea293a34fee20d46f90ec2bf3c1bd86c11b3597bb809' 
  AND token = '4q0pa7KKXWEiTJ68BoUR0R4bQo9ehZDwQy0CfjB5c+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}