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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '564b7ee58a49a451e58aa2bf66ed603031c43215d9ca6081d863a15a5a8c78d5' 
  AND token = 't4D8XQRj5Hl9/G9M9AHNrhHFNxh3MFUIn+roIZSozDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}