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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c95744521073bce0dad092f40f04c6e24bc725c5130da2138301d44da35658' 
  AND token = 'QM7Rzu/53mKgNNoCU7xlzfx6M1AZvq2mdmb7MVsbj6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}