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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86cc01beae0e38c59b04b5e1eef2a7f8f197d7cfe0d38dccb564b3dc54a18971' 
  AND token = '6Ij2xgqKwsu1aYPnzk6Qm75xXwVDZNsT5o91XR2wtjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}