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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '157afc28d1bede6c8824723bd02de24bece9ab12688b6b9ef566201ef7d43225' 
  AND token = '2bkTH+V+udLtcTvBj5LOcIwNbC7Mb1Oj7LHxRM22hds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}