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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '141c083eef1d5558076669a922824a0e0a2c983a04b3e1a166ad0abc69f31455' 
  AND token = 'aVVzoDZGlJVbLk5Mb0a3G9EExBpU9vuJbXfWkB0OU8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}