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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f9a1d9fe07a21eb7ee34b9ee9a362ae69dcf90ef5360235b02a05b68b692072' 
  AND token = 'DtBM0Kh5fPDe+ewjUZ5uE1a4f+hUiW32UECJxvY4BT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}