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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50a9c92b46ad69a4ccad626bd27e2ca93d3dcc52b66e7a7a42fc5574839e2b6' 
  AND token = 'N+NIofvQXcptevuflbNCPw6xQOY+22KraQddZzS90vU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}