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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d00eaf9515aa0514b823a038716d6b81ecfd7590dd47c520af3530dfd58f427' 
  AND token = 'aO8mllEy4ycgd355qG7LpKBtGyR6qYkiKUYOsY8qsbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}