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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdaadf429cd80c5b13efaafb664e8aa317abf5e9a28fc851c0f9c7a041e9b257' 
  AND token = 'Rx3SG2FtDh4LFs7RGmizkrJR0nHxDcu6JQJMvwxb8Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}