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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e21cf0ec0c4c6a7dca3cf0f937a2ca4d5429b8af9c76b525263454fe2c0bcb8' 
  AND token = '2E89rFlHkFCsSEqQAa8M5LGYBPEWVYPgHddpPOTJz6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}