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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a1a67b1c1eab2c7e095b386bd5e956c7b999c2860739dc3e6463a3aebdfca20' 
  AND token = 'GUl9yiXBLIbPpOWzUaFimd3hrCSY89BV6HF+CIvZwd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}