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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4e2bdc294b41506f31e50bba93e2cd36c0f5ef481ce5b373d512bf066920f2' 
  AND token = '1jRLv73tAqkPuMI/CTdxqn6bC1rFcXTWKs3xBgT0vP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}