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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aac73c0b7261eb3377aa99bd56b67ad17d67b90253aa4fd4cae242a7716198e1' 
  AND token = 'GptE0vmcB9qWiNE3I0QXREVhIaGJQhXPIgZxdVPrLuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}