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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff21bf4b1c1480888c58427c27fd4db1f9940fee1d8223ad0c3b0d77a1d390d6' 
  AND token = 'O7pdOoyaO0w4yHIPuMxu0IiS3g8yAfsMFf51amQNljQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}