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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '045c1443f7adfa9fb3a98f8e34623cec207beea5903beee7dc4a495b0290efc9' 
  AND token = 'IUp30VZUX490uKxOTZSUJJA5yTAv9SDw+AvQ2p4BWQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}