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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '770a97a61cbc193966813600af6cf86a42890f8b7fe0d125936b7c65da2f9b91' 
  AND token = 'RQbqq8YTSgMXOPW+UtbIkkCEQzw4VmTl4N2cz6cMWqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}