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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e643b492b3fa6c97086693872016e3781405d40f5e3a7b8d66390278fae8a74' 
  AND token = 'nnNp8oOPVf0VQaYn8QcVo/JvMcKzBMClZPkRESIfbxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}