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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e349f9cb43d9b409f84b70512a3cdde0d6a283801b4286bbbfa554368c36155' 
  AND token = '/QOSHI1NLTlhsZCosDTqS/ZKs+eoL2rMw6oZ/C4ekDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}