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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e28275e4269fcc744a6546294a1a6745b7eb822792cea0a9c54359df56cbb24' 
  AND token = '4bnmH2bNg/Jpr6i0IjCLKsAuQFeGclXu/nUUPTthf6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}