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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4690c61c7edcbdcb1d42be8edb24a81c2a11a34c7b8d7be40532c96cfdf73b67' 
  AND token = 'DzG/fIVjpVx0SPmRzlt7j6d9YyBCXY+WCO/jmj9NFBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}