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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cc440cc429227064a073e0e0d99bf2b5c25807dbfd9bd779a3a56f8d6a3bac9' 
  AND token = 'YRUQ0CbNisERP+xDMA7dGIHKTVOXT/gZa0p+A+qGQ6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}