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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4736a2e6db148adaed2a616df7ddac93f99a5a81ff6e9a91ec304761575d4ad' 
  AND token = 'eH9yj91/9ZHcWNGMcMo/UAUIg4tYZFfxXcXFHyNffoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}