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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a54e50f4413b755a891226052c7e8f9bbf193674213730ddc339a726d367a68' 
  AND token = '17EHT0EMq6yLPcSFnu1JeS4ZLzoRRTgRY+ZmxPYk8GQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}