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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1caac5283f26b4e1c0a64b7dbd80ed4f0d4cd2e7e0a110e5c1811f2a07e7c34b' 
  AND token = 'm+smCUJsPxRAvFg8/e6YYNXM/4Aye+7G2WZkCWwv4cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}