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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '275f8e5c8abb310c7024b1b5365e4141136361ae85ad9e1a11446a657c84d109' 
  AND token = 'utz43xRh7AcJ+0ewb81e88N1kIk8EKRJ+3bvMyKfRro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}