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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39a1eaf32304b4394ec9cc636a38d46ed3e06f925bfdf14e40ff4f1049f9b749' 
  AND token = 'HFzg65s+Cbx3TMVh6SvxT4d6KRoJjDMi4ivHLNW729I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}