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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc8122c6c76eab88e893561caf6b172eba04bfb01f3238beefb6e787b073bb65' 
  AND token = 'rMg1F3UWu/wNRSkiXxPjhlj9hPqgythbRJNtxOOrAfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}