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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e3c8ff2aacc9c89883465ba417735bcb8caca78b22d8c142840881a81e8b7b1' 
  AND token = 'BWVkvlniEDH8VaVKIiuhMrmuUXRIkxko0Je6WwqjrUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}