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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdf1672591a65b91c58aa6a258bf62739d4f2f32ffdd8f4d9081ee40a2e9e24b' 
  AND token = '4AVNTSY18yCCEFrG8RIrPTEFDcwyn5rGUTbelFqY4As=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}