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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f3ac87141ac7aab0e4b20510511ca66d8fe105febb744c37e65f9342e08c40a' 
  AND token = 'O3a1QNG2uX3YqMfzanEg5grsnQBGIeUgUBSy0T96FYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}