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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8253bd3c27ec2038dc6829541921ff091e5f8768047915a4ec44e705be76188f' 
  AND token = 'B4S5TVLEAaSag+QR78WdZsY2OFeibS7AQELUY/hZREE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}