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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12c3c96692395e7a6e5edd5d4a597db0007b8b269c6367ed42d7e59f7c2af6cd' 
  AND token = 'yU7/WUUg7R3vZGFV1kYVRoSLKCkiIs2+bY3oqlbx2wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}