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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99c08ace1e1242dd01595435acb6d93e86750a1944aa631643d886acc0900fd7' 
  AND token = 'Xmlet8vqAiZNrWgajZz4hj7qsFHHvwDNSmnbLdyGaEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}