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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bea1e5d34b3dcf3e82cd1b352618db973118a31b21f5841474ddadb312ab009' 
  AND token = 'l+a8o6ZbE1Acr5eO05IC4uLUzdQ4rZbGFUjXYDPWao0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}