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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f441525522869d13f2fc4b0a64eeafede7a3e4f15ce4186b52aceaee7c551e2e' 
  AND token = 'kpg0o1VfjLGtYeZ56w+Y6pDD5gtzzEkB2W5dZrhDiJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}