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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01df85fd17c2301185eee76902f4df5147b091e2fd9a6b69ea775d7c3d26ba1f' 
  AND token = 'T/PTD2s4B4qXEWrJODDld9GFF7V+m5o2zBk6QT4wEHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}