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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c146f7a55ed0a78d5b6797d9cb4309edab69fd3e06a5aff5280efee3ddf2d3e' 
  AND token = 'd5sY6j6oiqEPAQ6zGmSsng+i6uOJm3xfsV2pHIQVSvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}